Lymphoproliferative syndrome with positive Epstein-Barr virus and autoimmunity
DOI:
https://doi.org/10.32818/reccmi.a10n2a10Keywords:
lymphoproliferative syndromes, antinuclear antibodies (ANA), systemic lupus erythematosus, hemophagocytic lymphohistiocytosisAbstract
We present a 75-year-old male with constitutional syndrome and lymphadenopathy. Studies showed organomegaly, bicytopenia, and positive lupus serology, creating a diagnostic dilemma between lymphoma and autoimmune disease. The condition was complicated by secondary hemophagocytic syndrome. The lymph node biopsy
was diagnostic for an EBV-positive B-cell lymphoma. This case underscores the importance of correct clinical and laboratory correlation to avoid diagnostic errors in complex conditions, where positive autoimmunity can be a confounding factor.
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