Favorable outcome of classic Kaposi's sarcoma with expectant management

Authors

  • Dalit Zajdman-Faitelson Dermatology, Ángeles Lomas Hospital, Huixquilucan, State of Mexico, Mexico https://orcid.org/0000-0002-8195-6690
  • Fernando de la Barreda-Becerril Dermatology, Ángeles Lomas Hospital, Huixquilucan, State of Mexico, Mexico https://orcid.org/0000-0001-8483-5555
  • Sonia Toussaint-Caire Department of Dermatopathology, Dr. Manuel Gea González General Hospital, Mexico City, Mexico https://orcid.org/0000-0002-6883-3100
  • Fernando Pérez-Zincer Hemato-oncology, Ángeles Lomas Hospital, Huixquilucan, State of Mexico, Mexico

DOI:

https://doi.org/10.32818/reccmi.a10n2a11

Keywords:

classic Kaposi's sarcoma, human herpesvirus 8

Abstract

Kaposi's sarcoma is a vascular neoplasm associated with human herpesvirus 8. Its classic variant primarily affects elderly individuals of European origin and is characterized by violaceous macules and nodules on the lower extremities, usually asymptomatic and with an indolent course. We present the case of a 91-year-old woman with violaceous and brown macules and nodules, as well as lower limb edema, with a six-month evolution. A skin biopsy confirmed the diagnosis of classic Kaposi's sarcoma. Due to the absence of systemic involvement, no active treatment was initiated, and the patient was monitored clinically, showing near-complete resolution of the lesions after three months of follow-up.

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References

Cesarman E, Damania B, Krown SE, Martin J, Bower M, Whitby D. Kaposi sarcoma. Nat Rev Dis Primer. 2019; 5(1): 9. doi: https://doi.org/10.1038/s41572- 019-0060-9 (último acceso ago. 2025). DOI: https://doi.org/10.1038/s41572-019-0060-9

Brambilla L, Genovese G, Berti E, Peris K, Rongioletti F, Micali G, et al. Diagnosis and treatment of classic and iatrogenic Kaposi’s sarcoma: Italian recom-mendations. Ital J Dermatol Venereol. 2021; 156(3): 356-65. doi: https://doi. org/10.23736/S2784-8671.20.06703-6 (último acceso ago. 2025). DOI: https://doi.org/10.23736/S2784-8671.20.06703-6

Gupta K, Tun A, Gupta A, Berkowitz LB, Anwar R, Liu Y, et al. A case of classic Kaposi sarcoma in an immunocompetent human immunodeficiency virus–negative Dominican man. SAGE Open Med Case Rep. 2020; 8: 2050313X20938249. doi: https://doi.org/10.1177/2050313X20938249 (último acceso ago. 2025). DOI: https://doi.org/10.1177/2050313X20938249

Ramírez K, Zavala J, Morán D, Hernández D, Jiménez A. Classic Kaposi’s sarcoma - complete response to radiation therapy: a case report. J Med Case Reports. 2016; 10(1): 322. doi: https://doi.org/10.1186/s13256-016-1101-6 (último acceso ago. 2025). DOI: https://doi.org/10.1186/s13256-016-1101-6

Qian YT, Ma DL. Atypical presentation of classic Kaposi’s sarcoma. The Lancet. 2019; 393(10190): 2521. doi: https://doi.org/10.1016/S0140- 6736(19)31148-1 (último acceso ago. 2025). DOI: https://doi.org/10.1016/S0140-6736(19)31148-1

Attwa E, Gharib K, Albalat W, Amer A. Classical Kaposi sarcoma: case reports with unusual presentation on the penis and scrotum. Int J Dermatol. 2016; 55(10): e533-8. doi: https://doi.org/10.1111/ijd.13319 (último acceso ago. 2025). DOI: https://doi.org/10.1111/ijd.13319

Jang YH, Choi YH, Kim JY, Kim HY, Lee WJ, Lee SJ, et al. Classic type of Kaposi’s sarcoma showing spontaneous regression. Korean J Dermatol. 2011; 49(7): 625–8. Accesible en: https://www.koreamed.org/SearchBasic. php?RID=2247574 (último acceso ago. 2025).

Brenner B, Rakowsky E, Katz A, Gutman H, Sulkes A, Schacter J, Fenig E. Tailoring treatment for classical Kaposi's sarcoma: comprehensive clinical guidelines. Int J Oncol. 1999; 14(6): 1097-102. doi: https://doi.org/10.3892/ ijo.14.6.1097 (último acceso ago. 2025).

Published

2025-08-26

How to Cite

1.
Zajdman-Faitelson D, de la Barreda-Becerril F, Toussaint-Caire S, Pérez-Zincer F. Favorable outcome of classic Kaposi’s sarcoma with expectant management. Rev Esp Casos Clin Med Intern [Internet]. 2025 Aug. 26 [cited 2025 Sep. 4];10(2):75-7. Available from: https://www.reccmi.com/RECCMI/article/view/1189